What is the role of lab tests in the pretreatment evaluation for menopausal hormone replacement therapy (HRT)?

Updated: Sep 13, 2021
  • Author: Nicole K Banks, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Required baseline investigations are as follows:

  • Hemography

  • Urinalysis

  • Evaluation of the fasting lipid profile

  • Measurement of blood sugar levels

  • Electrocardiography

  • Papanicolaou test

  • Ultrasonography to measure endometrial thickness and ovarian volume

  • Mammography, which is performed once every 2-3 years and annually after the age of 50 years (see Mammography - Computer-Aided Detection)

  • Determination of serum estradiol levels in women who will be prescribed an implant and in women whose symptoms persist despite use of an adequate dose of a patch or gel

  • Determination of serum follicle-stimulating hormone (FSH) levels: FSH values may be used to monitor women who are taking oral preparations for symptomatic control, especially those with premature menopause.

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