How does menopause affect the vasomotor system?

Updated: Sep 24, 2019
  • Author: Nicole K Banks, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Answer

Answer

Vasomotor instability is the most common presenting symptom noted in postmenopausal women. Its exact cause is not yet known, but it is believed to be mediated at the level of the hypothalamus. Estrogen plays a role in thermoregulation by modulating the levels of neurotransmitters in the CNS. During menopause, diminished levels may lead to instability in the normal concentration of these transmitters, which manifests as hot flashes (hot flushes), night sweats, and excessive perspiration.


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