What are the possible transient adverse effects of menopausal hormone replacement therapy (HRT)?

Updated: Sep 13, 2021
  • Author: Nicole K Banks, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Adverse effects and risks

Possible transient adverse effects are as follows:

  • Nausea

  • Bloating, weight gain (equivocal finding), fluid retention

  • Mood swings (associated with use of relatively androgenic progestogens)

  • Breakthrough bleeding

  • Breast tenderness

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