How are endometrial changes assessed in menopausal women?

Updated: Jun 06, 2018
  • Author: PonJola Coney, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Endometrial assessment

Endometrial biopsy can show a range of endometrial appearances, from mildly proliferate to atrophic. No secretory changes are observed after menopause, because no ovulation occurs and therefore no corpus luteum forms to produce progesterone.

Endometrial hyperplasia is a sign of hyperstimulation by estrogen from either endogenous sources or replacement therapy and may be a precursor of endometrial cancer. Endometrial hyperplasia can also be suggested by ultrasonographic findings (ie, endometrial thickness > 5 mm), which are useful for excluding hyperplasia and cancer of the endometrium in postmenopausal women.

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