What is the role of calcium/vitamin D supplementation in the treatment of menopausal women?

Updated: Jun 06, 2018
  • Author: PonJola Coney, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Postmenopausal calcium/vitamin D supplementation appears to increase serum 25-hydroxyvitamin D3 (25OHD3) levels and improve lipid profiles. When Schnatz et al evaluated the effect of increased levels of 25OHD3 from calcium/vitamin D supplementation on the lipid profiles of 600 postmenopausal women randomly selected from the Women’s Health Initiative Calcium/Vitamin D Trial, they found that daily supplementation with 1,000 mg of elemental calcium and 400 IU of vitamin D3 significantly increased concentrations of 25OHD3 and decreased levels of low-density lipoprotein cholesterol. [35] Moreover, women with higher concentrations of 25OHD3 had higher levels of high-density lipoprotein cholesterol but lower triglyceride levels. [35]

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