Which medications are used to treat osteoporosis in menopausal women?

Updated: Jun 06, 2018
  • Author: PonJola Coney, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Currently, there are many treatment options for preventing fractures among postmenopausal women with osteoporosis, including the following:

  • Bisphosphonates

  • Selective estrogen receptor modulators (SERMs)

  • Calcium

  • Vitamin D

  • Calcitonin

  • Monoclonal antibodies

  • Hormonal medications

  • Estrogen therapy (considered a second-line therapy for osteoporosis [5] )

Variations in osteoporosis care are common among physicians. Whereas the majority of patients receive bisphosphonates, younger patients who have fewer comorbidities or are cared for by physicians with greater experience have a greater chance of receiving SERMs, hormone replacement therapy, or calcium and vitamin D. [28] Oral and transdermal estrogen preparations have been approved for osteoporosis prevention in postmenopausal women who are considered at risk.

Bone loss accelerates in the late menopausal transition and continues for the first few years after menopause. [4] Postmenopausal women and elderly women should be treated early and on a long-term basis unless a contraindication to such treatment exists.

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