Which factors may lower the age of menopause

Updated: Jun 06, 2018
  • Author: PonJola Coney, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Although the time spent in menopause (now up to one third of the life cycle) has increased, the average age at which menopause occurs, approximately 50-51 years, has not changed since antiquity. Women from ancient Greece experienced menopause at the same age as modern women do, with the symptomatic transition to menopause usually commencing at approximately age 45.5-47.5 years. [3, 9] Factors that can lower the age of physiologic menopause include the following:

  • Smoking [9, 10]

  • Hysterectomy

  • Oophorectomy

  • Fragile X carrier

  • Autoimmune disorders

  • Living at high altitude

  • History of receiving certain chemotherapy medications or undergoing radiotherapy

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