What are the contraindications for HRT to treat menopausal symptoms?

Updated: Jun 06, 2018
  • Author: PonJola Coney, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Contraindications for estrogen therapy include the following:

  • Undiagnosed vaginal bleeding

  • Severe liver disease

  • Pregnancy

  • Venous thrombosis

  • Personal history of breast cancer

Well-differentiated and early endometrial cancer, once treatment for the malignancy is complete, is no longer an absolute contraindication. Progestins alone may relieve symptoms if the patient is unable to tolerate estrogens.

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