What is the role of dietary interventions and supplements in the prevention of preeclampsia?

Updated: Jun 12, 2018
  • Author: Michael P Carson, MD; Chief Editor: Edward H Springel, MD, FACOG  more...
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Multiple dietary interventions and supplements have been investigated for a role in preventing preeclampsia, but none has shown any consistent beneficial effect. One trial demonstrated some preventive benefit to supplemental antioxidants (vitamins C and E), but a 2008 review found that the evidence did not support routine use of antioxidants for this purpose. [34] In 2010, Roberts et al reported the outcome data for nearly 1000 nulliparous women in which no significant differences between vitamin and placebo groups were observed in reducing the rate of adverse maternal or perinatal outcomes related to pregnancy-associated hypertension. [35] The study was a multicenter, randomized, double-blind trial of nulliparous women at low risk for preeclampsia.

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