Which medications in the drug class Cytoprotective Agents are used in the treatment of Ovarian Cancer?

Updated: Aug 10, 2020
  • Author: Andrew E Green, MD; Chief Editor: Yukio Sonoda, MD  more...
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Answer

Cytoprotective Agents

Mesna is indicated in the prevention of hemorrhagic cystitis in patients being treated with ifosfamide and cyclophosphamide.

Mesna (Mesnex)

Mesna detoxifies metabolites of ifosfamide and cyclophosphamide. Usage is somewhat controversial, but it is commonly accepted that the total dose should be at least 60% of the total dose of the alkylating agent.


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