What are the ACOG criteria for ovarian cancer workup?

Updated: Aug 10, 2020
  • Author: Andrew E Green, MD; Chief Editor: Yukio Sonoda, MD  more...
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Answer

The American College of Obstetricians and Gynecologists has established referral guidelines for a patient with a newly diagnosed pelvic mass. Women who meet the criteria below would benefit from preoperative consultation with a gynecologic oncologist. [123]

For premenopausal women, referral criteria are as follows:

  • CA-125 level greater than 200 units/mL
  • Ascites
  • Evidence of abdominal or distant metastasis (on examination or imaging study)
  • Family history of breast or ovarian cancer in a first-degree relative

For menopausal women, referral criteria are as follows:

  • Elevated CA-125 levels (any degree of elevation)
  • Ascites
  • Nodular or fixed pelvic mass
  • Evidence of abdominal or distant metastasis (on examination or imaging study)
  • Family history of breast or ovarian cancer in a first-degree relative

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