What is the role of ERT in the treatment of ovarian cancer?

Updated: Aug 10, 2020
  • Author: Andrew E Green, MD; Chief Editor: Yukio Sonoda, MD  more...
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Answer

The safety of estrogen replacement therapy (ERT) after treatment for epithelial ovarian cancer has not been tested in a randomized trial, but current evidence suggests that the benefits of ERT outweigh the risks.

In younger women with endometrioid subtypes, ERT is a concern because these tumors theoretically are estrogen sensitive. If estrogen is used in such patients, a progestin should also be considered.


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