Which medications in the drug class Uroprotective agents are used in the treatment of Granulosa-Theca Cell Tumors?

Updated: Aug 30, 2018
  • Author: David C Starks, MD, MPH; Chief Editor: Warner K Huh, MD  more...
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Answer

Uroprotective agents

Prevention of hemorrhagic cystitis in patients being treated with ifosfamide and cyclophosphamide.

Mesna (Mesnex)

Detoxifies metabolites of ifosfamide and cyclophosphamide.

Somewhat controversial but commonly accepted that total dose should be at least 60% of total dose of alkylating agent.


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