What are the guidelines for endometrial carcinoma screening?

Updated: Jun 19, 2018
  • Author: William T Creasman, MD; Chief Editor: Warner K Huh, MD  more...
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Currently, no major organization recommends screening for cancer of the uterus for asymptomatic women. According to the National Cancer Institute (NCI) PDQ cancer information summary for endometrial cancer screening, no evidence suggests that transvaginal sonography reduces mortality from endometrial cancer, and there is inadequate evidence that endometrial sampling (biopsy) reduces mortality. The early clinical presentation and high early detection rate (85%) make it unlikely that screening will have a successful impact on earlier detection and increased survival rate. [19]

The American Cancer Society (ACS) recommends that at the time of menopause, all women should be made aware of the risks and symptoms of endometrial cancer and strongly encouraged to report any unexpected bleeding or spotting to their physician. [20]

Additionally, the NCI’s PDQ cancer information summary and ACS agree that for women at increased risk for endometrial cancer due to a history of receiving either estrogen therapy or tamoxifen therapy, there is no indication that routine screening would improve early detection or survival rates. As with women at average risk, these women generally present with symptoms at an early stage when the prognosis is good. [19, 20]

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