What is the histopathology and degree of differentiation of endometrial carcinoma?

Updated: Jun 19, 2018
  • Author: William T Creasman, MD; Chief Editor: Warner K Huh, MD  more...
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Answer

Cases of carcinoma of the corpus should be classified (or graded) according to the degree of histologic differentiation. The histopathology and degree of differentiation is as follows:

  • Class G1 - Nonsquamous or nonmorular solid growth pattern of 5% or less

  • Class G2 - Nonsquamous or nonmorular solid growth pattern of 6-50%

  • Class G3 - Nonsquamous or nonmorular solid growth pattern of more than 50%

* Either G1, G2, or G3.

** Endocervical glandular involvement only should be considered as Stage I and no longer as Stage II.

† Positive cytology has to be reported separately without changing the stage.


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