Which congenital abnormalities cause hypogonadotropic hypogonadism amenorrhea?

Updated: Oct 14, 2019
  • Author: Kristi A Tough DeSapri, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Congenital abnormalities that can cause hypogonadotropic hypogonadism include the following:

  • Isolated GnRH deficiency (8.3%)

  • Forms of hypopituitarism (2.3%)

  • Congenital central nervous system (CNS) defects (0.8%)

  • Constitutional delay (6%)

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