What are the MASCC/ESMO treatment guidelines for radiation-induced nausea and vomiting (RINV)?

Updated: May 31, 2018
  • Author: Winston W Tan, MD, FACP; more...
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Multinational Association for Supportive Care in Cancer/European Society for Medical Oncology (MASCC/ESMO) recommendations for patients receiving radiation therapy (RT) are keyed to risk level, and include the following [2] :

  • High-risk RT: : 5-HT3 RA + DEX
  • Moderate-risk RT: 5-HT3 RA; short course of DEX is optional
  • Low-risk RT to cranium: DEX as either prophylaxis or rescue
  • Low-risk RT to head and neck, thorax region, pelvis: DEX, DOP, or 5-HT3 RA as either prophylaxis or rescue
  • Minimal-risk RT: Rescue with DEX, DOP, or 5-HT3 RA

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