What are the ASCO/IDSA guidelines for outpatient management of fever in neutropenic cancer patients?

Updated: Sep 16, 2018
  • Author: Alexandre Chan, PharmD, MPH, FCCP, BCPS (AQ-ID), BCOP; more...
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The ASCO/IDSA guideline recommendations for outpatient management of fever and neutropenia in adult cancer patients are as follows:

  • In the absence of an alternative explanation, clinicians should assume that fever in a patient with neutropenia from cancer therapy is the result of an infection. 
  •  Fever in neutropenic patients is defined as a single oral temperature of ≥ 38.3°C (101°F) or a temperature of ≥ 38.0°C (100.4°F) sustained over 1 hour.
  • Patients who present with febrile neutropenia within 65 weeks after receiving chemotherapy should be assessed within 15 minutes after triage.

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