How is the typical course of Zika virus infection characterized?

Updated: Jun 30, 2021
  • Author: Bhagyashri D Navalkele, MD, MBBS; Chief Editor: Michael Stuart Bronze, MD  more...
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Most cases of Zika virus infection are mild and self-limited. Owing to the mild nature of the disease, more than 80% of Zika virus infection cases likely go unnoticed. [2]  

Serious neurological complications have been reported in rare cases, including Guillain-Barré syndrome. [2, 21]

In addition, adverse pregnancy outcomes and congenital Zika syndrome due to vertical transmission of Zika virus is of greatest concern with poor long-term prognosis. [14, 22]  

Zika virus infection has short-term adverse effects on fertility.

For more details, see History.

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