What are the variations of the Framingham Risk Score (FRS)?

Updated: Nov 30, 2018
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The 2002 adaption deleted the variables of diabetes and family history of premature coronary heart disease (CHD), added the impact of treatment for hypertension, and used only hard coronary heart disease endpoints in its calculations. [2]

The 2008 adaption included additional cardiovascular events (ie, stroke, transient ischemic attack) that had not previously been assessed. The 10-year CVD risk score is expected to be higher than the 10-year CHD risk score. [3]

The 2006 Lifetime-FRS estimates risk from age 50 based on four risk factors: total cholesterol, systolic blood pressure, cigarette smoking, and diabetes. [4]  The 2014 International Atherosclerosis Society (IAS) guidelines recommends the 2006 Lifetime-FRS for countries where recalibration values can be applied to risk calculations. [5]

The 2009 30-year FRS-HCVD estimates risk from age 45 based on a larger number of major risk factors and uses only hard disease endpoints. [6]

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