What are the ENETS guidelines on the treatment of neuroendocrine tumors (NETs) of the bowel?

Updated: Dec 23, 2018
  • Author: Evan S Ong, MD, MS; more...
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The ENETS guidelines provide following recommendations [16, 17] :

Rectal tumors [16]

  • Endoscopic resection by simple polypectomy, endoscopic mucosal resection (EMR) with modified EMR band ligation, endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEMS).

  • For lesions < 10 mm and no involvement of the muscularis propria, EMR is adequate, but EMR band-assisted ligation may improve the number of complete resections 

  •  If EMR results in an incomplete resection, then ESD or TEMS may be indicated as salvage therapy

 Jejunum and ileum tumors [17]

  • Curative resection of the primary tumor and dissection of the locoregional lymph node metastasis along the superior mesenteric root and around the mesentery
  • Lymphatic mapping is not a standardized procedure and is not generally recommended 

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