What are the NANETS guidelines on the treatment of neuroendocrine tumors (NETs) of the bowel?

Updated: Dec 23, 2018
  • Author: Evan S Ong, MD, MS; more...
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The NANETS guidelines include the following recommendations [14] :

  • Tumors of the cecum: Right hemicolectomy with node dissection

  • Tumors of the jejunal or ileum: Resection with node dissection; full bowel examination required

  • Distal colon and rectum tumors < 1 cm: Endoscopic resection (polypectomy, endoscopic mucosal resection, endoscopic submucosal dissection) for mucosal or submucosal tumors

  • Distal colon and rectum tumors 1-2 cm: Transanal excision via rigid or flexible dissection; could also be considered after endoscopic resection with positive margins

  • Distal colon and rectum tumors >2 cm: Surgical resection (low anterior resection or abdominoperineal resection) for larger tumors, tumors invading muscularis propria, or those with lymphadenopathy

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