What causes exercise-induced hyponatremia?

Updated: Aug 16, 2019
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Exercise-induced hyponatremia has been reported during prolonged exercise such as in marathon runners and triathletes, usually in warmer climates, which can lead to severe hyponatremia associated with neurological symptoms. [22] The syndrome appears to arise because of excessive water consumption during the physical exercise coupled with loss of sodium chloride in sweat and nonosmotic stimulation of AVP secretion (from stress, volume contraction, nausea, and nonsteroidal anti-inflammatory drugs [NSAIDs]). Some athletes with cerebral edema also develop noncardiogenic pulmonary edema. [15]

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