What are the treatment options for abscesses in patients with acute pyelonephritis (kidney infection)?

Updated: Jul 01, 2021
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

For renal cortical abscesses (renal carbuncles), surgical drainage was once the only treatment. However, modern antibiotics alone often are curative. A semisynthetic penicillin, cephalosporin, fluoroquinolone, or vancomycin is recommended. Generally, parenteral antibiotics should be administered for 10-14 days, followed by oral therapy for 2-4 weeks. Fever should resolve within 5-6 days, and pain should resolve within 24 hours. If parenteral antibiotic therapy is successful, oral therapy is instituted for an additional 2-4 weeks.


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