When should the empirical use of TMP-SMZ be avoided for treatment of acute pyelonephritis (kidney infection)?

Updated: Jul 01, 2021
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print

Because of the high rate of resistance of E coli, the empirical use of TMP-SMX should be avoided in patients who require hospitalization. If beta-lactam drugs and fluoroquinolones are contraindicated, administer aztreonam parenterally. As such, the patient will need to be admitted.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!