What are the IDSA recommendations for inpatient treatment of women with pyelonephritis (kidney infection)?

Updated: Jul 01, 2021
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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The 2010 guidelines from the Infectious Disease Society of America (IDSA) recommend that women with pyelonephritis who require hospitalization be treated initially with an intravenous antimicrobial regimen. The choice of antimicrobial agents should be based on local resistance data, with the regimen tailored on the basis of susceptibility results. [3]

Although the guidelines recommend either 14 days of TMP-SMX or 7 days of ciprofloxacin for the treatment of pyelonephritis, a study in 272 women with susceptible E coli pyelonephritis reported similar clinical outcomes with 7 days of TMP-SMX therapy compared with 7 days of ciprofloxacin. [30]

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