Which antibiotics should be used to treat community-acquired acute pyelonephritis (kidney infection)?

Updated: Jul 01, 2021
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The pathogen in community-acquired infections is usually Escherichia coli or other Enterobacteriaceae. Acceptable regimens may include fluoroquinolones, cephalosporins, penicillins, extended-spectrum penicillins, carbapenems, and aminoglycosides. [24, 3] If enterococci are suggested on the basis of Gram stain results, ampicillin or vancomycin can replace the fluoroquinolone. If any doubt exists as to the diagnosis, coverage of both Enterobacteriaceae and enterococci is acceptable.


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