What are the histologic findings of acute pyelonephritis (kidney infection)?

Updated: Jul 01, 2021
  • Author: Tibor Fulop, MD, PhD, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Features of acute pyelonephritis include suppurative necrosis or abscess formation within the kidney substance. In contrast, features of chronic pyelonephritis (chronic interstitial nephritis) include the following:

  • Papillary atrophy and blunting
  • Interstitial fibrosis with inflammatory infiltrate (ie, lymphocytes, plasma cells, neutrophils [occasional]), tubule changes (ie, dilated with possible colloid casts, contracted with atrophy of epithelium), and concentric fibrosis around the parietal layer of the Bowman capsule

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