What is the treatment of choice for renal artery fibromuscular dysplasia?

Updated: Nov 02, 2020
  • Author: Bruce S Spinowitz, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

PTA is the treatment of choice for renal artery fibromuscular dysplasia. A retrospective analysis by Yang et al of 76 PTA procedures in 64 patients reported that in the majority of cases (79.7%) the patient experienced immediate clinical benefit, with cure of hypertension in 35.9% and improvement in hypertension and a lower requirement for antihypertensive medications in 43.8%. In the long term (mean, 47.5 months), the survival rate was 96.9%, freedom from restenosis was 84.4%, and 76.6% of patients showed a sustained clinical benefit (cure rate 40.6%, improvement rate 35.9%). [55]

Patients with restenosis showed good response to repeat PTA. Eight patients were treated with a second procedure and two had a third procedure, resulting in improvement in hypertension in half of those patients. [55]


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