What is the efficacy of surgical revascularization for renal artery stenosis (RAS)?

Updated: Nov 02, 2020
  • Author: Bruce S Spinowitz, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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In 1962, Morris et al compiled the first report on a surgical treatment for occlusion of the renal arteries. [30]  They described eight patients with renal failure who underwent revascularization. Six of these patients returned to essentially normal kidney function.

Reports from retrospective studies clearly document that surgical revascularization can improve renal function in patients with ischemic nephropathy. In 1993, Rimmer and Gennari reported postoperative improvement (ie, 20% decrease in serum creatinine concentration) in more than half the patients in nine studies. [31]  A long-term study (median follow-up, 10.6 years) of open surgical renal artery reconstruction that included 31 patients with stenosis reported low mortality, fairly low morbidity, and excellent durability and recommended that open surgery remain an option for patients with complex renal artery disease. [32]


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