What is the role of blood oxygen level–dependent (BOLD) MRI in the workup of renal artery stenosis (RAS)?

Updated: Nov 02, 2020
  • Author: Bruce S Spinowitz, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Blood oxygen level–dependent (BOLD) MRI is a noninvasive technique for evaluating kidney tissue oxygenation that requires no contrast exposure and has the potential to allow functional assessment for patients with atherosclerotic renal artery stenosis. Although a decrease in renal blood flow does not invariably lead to renal hypoxia, severe vascular occlusion can overwhelm the kidney's capacity to adapt to reduced blood flow, and BOLD MRI has demonstrated renal cortical hypoxia in patients with severe renal artery stenosis. [23]


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