What is the role of surgery in the treatment of autosomal dominant polycystic kidney disease (ADPKD)?

Updated: Mar 24, 2020
  • Author: Roser Torra, MD, PhD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Surgical intervention in ADPKD includes the following:

  • Surgical drainage: Usually in conjunction with ultrasonographically guided puncture; in cases of infected renal/hepatic cysts not responding to conventional antibiotics

  • Open or fiberoptic-guided surgery: For excision/drainage of the outer walls of cysts to ablate symptoms

  • Nephrectomy: Last resort for pain control in patients with inaccessible cysts in the renal medullae; bilateral nephrectomy in patients with severe hepatic involvement

  • Partial hepatectomy: To manage massive hepatomegaly

  • Liver transplantation: In cases of portal hypertension due to polycystic liver or hepatomegaly with nonresectable areas

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