Which medications in the drug class Calcium Channel Blockers are used in the treatment of Acute Kidney Injury?

Updated: Dec 24, 2020
  • Author: Biruh T Workeneh, MD, PhD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Calcium Channel Blockers

These drugs are effective in animal models of AKI, but their efficacy has not been proven in humans. The effects of calcium channel blockers are believed to be mediated through vasodilation, and they are increasingly used to enhance the function of transplanted kidneys.

Nifedipine (Adalat, Procardia, Afeditab CR, Nifediac CC, Nifedical XL)

Nifedipine relaxes smooth muscle and produces vasodilation, which, in turn, improves blood flow and oxygen delivery.


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