How is the rise in creatinine predicted in the workup of acute kidney injury (AKI)?

Updated: Dec 24, 2020
  • Author: Biruh T Workeneh, MD, PhD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Assuming no renal function, the rise in creatinine can be predicted using the following formulas:

  • For males: Weight in kilograms × [28 - 0.2(age)] ÷ total body water, with the result in mg/dL added to the creatinine value

  • For females: Weight in kilograms × [23.8 - 0.17(age)] ÷ total body water, with the result in mg/dL added to the creatinine value

As a general rule, if serum creatinine increases to more than 1.5 mg/dL/day, rhabdomyolysis must be ruled out.

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