What are the etiologic factors for acute kidney injury (AKI)?

Updated: Dec 24, 2020
  • Author: Biruh T Workeneh, MD, PhD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

It is important to elicit a history of any of the following etiologic factors:

  • Volume restriction (eg, low fluid intake, gastroenteritis)
  • Nephrotoxic drug ingestion (eg, nonsteroidal anti-inflammatory drugs [NSAIDs], aminoglycosides) [39]
  • Exposure to iodinated contrast agents within the past week [39]
  • Trauma or unaccustomed exertion
  • Blood loss or transfusions
  • Exposure to toxic substances, such as ethyl alcohol or ethylene glycol
  • Exposure to mercury vapors, lead, cadmium, or other heavy metals, which can be encountered in welders and miners

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