How is acute kidney injury (AKI) treated?

Updated: Dec 24, 2020
  • Author: Biruh T Workeneh, MD, PhD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Maintenance of volume homeostasis and correction of biochemical abnormalities remain the primary goals of AKI treatment and may include the following measures:

  • Correction of fluid overload with furosemide

  • Correction of severe acidosis with alkali administration, which can be important as a bridge to dialysis

  • Correction of life-threatening hyperkalemia

  • Correction of hematologic abnormalities (eg, anemia, uremic platelet dysfunction) with measures such as RBC or platelet transfusions and administration of desmopressin or estrogens

Dietary changes are an important facet of AKI treatment. Restriction of salt and fluid becomes crucial in the management of oliguric renal failure, in which the kidneys do not adequately excrete either toxins or fluids.

Pharmacologic treatment of AKI has been attempted on an empiric basis, with varying success rates.

See Treatment and Medication for more detail.

For patient education information, see Acute Kidney Failure.

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