What formula is used to calculate glomerular filtration rate (GFR) in children with chronic kidney disease (CKD)?

Updated: Jul 21, 2021
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

GFR in children is calculated using the Schwartz formula (see Chronic Kidney Disease in Children). Because this formula may currently overestimate GFR, likely due to a change in methods used to measure creatinine, Schwartz et al have proposed an updated equation that includes cystatin C. [51] However, the majority of dosing guidelines for medication adjustments due to reduced GFR use the original Schwartz equations.


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