What is the Cockcroft-Gault formula for estimating creatinine clearance (CrCl) and how is it used in patients with chronic kidney disease (CKD)?

Updated: Jul 21, 2021
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The Cockcroft-Gault formula for estimating creatinine clearance (CrCl) should be used routinely as a simple means to provide a reliable approximation of residual renal function in all patients with CKD. The formulas are as follows:

  • CrCl (male) = ([140-age] × weight in kg)/(serum creatinine × 72)

  • CrCl (female) = CrCl (male) × 0.85


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