Which depression screening tools are effective in the evaluation of adult patients with chronic kidney disease (CKD) and when should they be used?

Updated: Jul 21, 2021
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Forty-five percent of adult patients with CKD have depressive symptoms at initiation of dialysis therapy, as assessed using self-report scales. However, these scales may emphasize somatic symptoms—specifically, sleep disturbance, fatigue, and anorexia—that can coexist with chronic disease symptoms.

Hedayati et al reported that the 16-item Quick Inventory of Depressive Symptomatology-Self Report (QIDS-SR[16]) and the Beck Depression Inventory (BDI) are effective screening tools and that scores of 10 and 11, respectively, were the best cutoff scores for identification of a major depressive episode in their study's patient population. [39] The study compared the BDI and QIDS-SR(16) with a gold-standard structured psychiatric interview in 272 patients with CKD stages 2-5 who had not been treated with dialysis.

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