How does chronic kidney disease (CKD) affect black patients differently from white patients?

Updated: Jul 21, 2021
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Although CKD affects all races, the incidence rate of ESRD among Blacks in the United States is nearly 4 times that for whites. [19] Choi et al found that rates of ESRD among Black patients exceeded those among white patients at all levels of baseline estimated glomerular filtration rate (GFR). [23] Risk of ESRD among Black patients was highest at an estimated GFR of 45-59 mL/min/1.73 m2, as was the risk of mortality.

Schold et al found that among Black kidney transplant recipients, rates of graft loss and acute rejection were higher than in white recipients, especially among younger patients. [24] Hicks et al looked at the connection between Black patients with the sickle cell trait and their increased risk for kidney disease; the study found that sickle cell trait was not associated with diabetic or nondiabetic ESRD in a large sample of Black patients. [25]

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