What are the indications for renal replacement therapy in chronic kidney disease (CKD)?

Updated: Jul 21, 2021
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Indications for renal replacement therapy include the following:

  • Severe metabolic acidosis
  • Hyperkalemia
  • Pericarditis
  • Encephalopathy
  • Intractable volume overload
  • Failure to thrive and malnutrition
  • Peripheral neuropathy
  • Intractable gastrointestinal symptoms
  • In asymptomatic patients, a GFR of 5-9 mL/min/1.73 m², [5] irrespective of the cause of the CKD or the presence or absence of other comorbidities

The National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (KDOQI) issued a Clinical Practice Guideline for Nutrition in Chronic Renal Failure, as well as a revision of recommendations for Nutrition in Children with Chronic Kidney Disease.

See Treatment and Medication for more detail.

For a discussion of CKD in children, click here.

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