What are acute manifestations of schistosomiasis (Katayama syndrome)?

Updated: Jun 11, 2020
  • Author: Shadab Hussain Ahmed, MD, AAHIVS, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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Individuals who have been exposed to fresh or salt water may develop a pruritic rash due to cercarial dermatitis (also called swimmer's itch). This has been described in North America as occurring via nonhuman avian schistosomes.

Patients with acute schistosomiasis (Katayama fever) present usually 4-8 weeks after contact with infested water. It occurs 2-8 weeks after exposure to S japonicum or S mansoni. Katayama fever is common in heavily infested areas where there is S japonicum. Wading and swimming in fresh water in tropical regions causes schistosomal trematodes to enter the body. Fever, lethargy, malaise, and myalgia are the most common symptoms of Katayama syndrome. Less common symptoms include cough, headache, anorexia, and rash (urticarial or papular). Right upper quadrant pain and bloody diarrhea may also occur. [38]

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