How is degree of illness determined in Pneumocystis jiroveci pneumonia (PJP)?

Updated: Apr 24, 2019
  • Author: Shelley A Gilroy, MD, FACP, FIDSA; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Treatment of PJP depends on the degree of illness at diagnosis. Degree of illness is determined based on the alveolar-arterial gradient: mild (< 35 mm Hg), moderate/severe (35-45 mm Hg), or severe (>45 mm Hg). Severe disease is also indicated by a room air partial pressure of oxygen lower than 70 mm Hg. Treatment of extrapulmonary manifestations of PJP is the same as that for other pneumonias.

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