What is the initial treatment for Legionnaires disease?

Updated: Mar 11, 2021
  • Author: Chinelo N Animalu, MD, MPH; Chief Editor: Michael Stuart Bronze, MD  more...
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A delay in treatment significantly increases the risk of mortality in Legionnaires disease (LD). Therefore, include empiric anti-Legionella therapy in the regimen for severe community-acquired pneumonia (CAP) and in specific cases of nosocomial pneumonia.

Although Legionella pneumonia can present as a mild illness, most patients require hospitalization with parenteral antibiotics. Most healthy hosts exhibit clinical response to treatment within 3-5 days.

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