What is the role of CT scanning in the workup of fever of unknown origin (FUO)?

Updated: May 17, 2021
  • Author: Sandra G Gompf, MD, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD  more...
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CT scanning of the abdomen and pelvis with intravenous and oral contrast is useful in the setting of hepatosplenomegaly looking for adenopathy, intraabdominal or psoas muscle hematoma or abscess, perinephric abscess, cholecystitis, or neoplasia. Plain abdominal films and ultrasonography are relatively insensitive in the diagnosis of FUO. In patients with hepatobiliary infections, cholangitis can occur without local signs and with only mildly elevated or normal findings on liver function tests.

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