What is the role of enterococci in the emergence of vancomycin-resistant S aureus (VRSA)?

Updated: Jun 10, 2021
  • Author: Susan L Fraser, MD; Chief Editor: John L Brusch, MD, FACP  more...
  • Print
Answer

Thirteen patients infected with vancomycin-resistant Staphylococcus aureus (VRSA) have been reported in the United States. [10, 11, 12] The in vivo conjugative transfer potential of the vanA resistance gene from vancomycin-resistant E faecalis to methicillin-resistant S aureus (MRSA) was confirmed in all of these cases. This poses an emerging threat to patient safety. E faecium isolates with a complex-17 lineage have also emerged in hospital and community settings in 5 continents over just the past 2 decades. This continued global spread of resistant organisms and the creation of new, highly virulent pathogens from transfer of resistance genes underscore the importance of infection control and prevention, active surveillance, and use of appropriate antibiotics.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!