What are the signs and symptoms of cytomegalovirus (CMV)?

Updated: Jul 07, 2021
  • Author: Ricardo Cedeno-Mendoza, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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CMV usually causes an asymptomatic infection or produces mild flulike symptoms; afterward, it remains latent throughout life and may reactivate.

Most patients with CMV infection exhibit few clinical findings on physical examination.

  • Primary CMV infection may be a cause of fever of unknown origin.

  • Symptoms, when apparent, develop 9-60 days after primary infection.

  • Pharyngitis may be present.

  • Examination of the lungs may reveal fine crackles.

  • The lymph nodes and spleen may be enlarged, so CMV should be included in the differential diagnoses of infections that produce lymphadenopathy.

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