What are the IDSA guidelines on the treatment of impetigo in children?

Updated: Jun 14, 2019
  • Author: Thomas E Herchline, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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In children (excluding neonates), the IDSA recommends the following antibiotic regimens, with treatment duration of about 7 days (based on the clinical response) [2] :

  • Mupirocin ointment applied topically tid in patients with a limited number of lesions

  • Dicloxacillin 12 mg/kg/day PO, in 4 divided doses

  • Cephalexin 25 mg/kg/day PO, in 4 divided doses

  • Erythromycin 40 mg/kg/day PO, in 4 divided doses

  • Clindamycin 10-20 mg/kg/day PO in 3 divided doses

  • Amoxicillin-clavulanate 25 mg/kg/day of the amoxicillin component PO in 2 divided doses

See also the Medscape Reference articles Cellulitis Organism-Specific Therapy, Cellulitis Empiric Therapy, Periorbital Cellulitis Organism-Specific Therapy, Periorbital Cellulitis Empiric Therapy, Orbital Cellulitis Organism-Specific Therapy, and Orbital Cellulitis Empiric Therapy.

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