What are cautions for the use of transdermal fentanyl?

Updated: Jan 29, 2018
  • Author: Stephen Kishner, MD, MHA; Chief Editor: Erik D Schraga, MD  more...
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See the list below:

  • Transdermal fentanyl is NOT recommended for breakthrough or unstable pain requiring frequent dosage adjustments.

  • Patches MUST NOT be used in opioid-naïve patients; they are indicated only for patients who are opioid tolerant.

  • Do not apply any external heat to patch; heat may increase absorption and increase risk of overdose.

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