How is meningitis treated in patients with brucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
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Third-generation cephalosporins have been used in Brucella meningitis, but susceptibility is variable and must be ensured by in vitro sensitivity studies. Duration of therapy has ranged in various cases from 1-19 months, with treatment continued until the cerebrospinal fluid (CSF) is found to be without evidence of organisms or inflammation. In the year following cessation of treatment, agglutinins for Brucella should be followed in serum to ensure that relapse does not occur.

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